S100B Antibody (4C4.9), Janelia Fluor™ 549, Novus Biologicals™

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NBP233168JF549

Catalog No. N233168J549

Description

S100B Monoclonal specifically detects S100B in Human, Mouse, Rat, Bovine samples. It is validated for Western Blot, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin.

Specifications

• Antigen: S100A1
• Classification: Monoclonal
• Conjugate: Janelia Fluor 549
• Formulation: 50mM Sodium Borate with 0.05% Sodium Azide
• Gene Symbols: S100A1
• Immunogen: Purified bovine brain S100B protein (Uniprot: P04271)
• Quantity: 0.1 mL
• Primary or Secondary: Primary
• Test Specificity: S100 belongs to the family of calcium binding proteins. S100A and S100B proteins are two members of the S100 family. S100A is composed of an alpha and a beta chain whereas S100B is composed of two beta chains. This antibody is specific against an epitope located on the beta-chain (i.e. in S-100A and S-100B) but not on the alpha-chain of S-100 (i.e. in S-100A and S100A0). This antibody can be used to localize S-100A and S-100B in various tissue sections. S-100 protein has been found in normal melanocytes, Langerhans cells, histiocytes, chondrocytes, lipocytes, skeletal and cardiac muscle, Schwann cells, epithelial and myoepithelial cells of the breast, salivary and sweat glands, as well as in glial cells. Neoplasms derived from these cells also express S-100 protein, albeit non-uniformly. A large number of well-differentiated tumors of the salivary gland, adipose and cartilaginous tissue, and Schwann cell-derived tumors express S-100 protein. Almost all malignant melanomas and cases of histiocytosis X are positive for S-100 protein.
• Content And Storage: Store at 4°C in the dark.

• Applications: Western Blot, ELISA, Immunohistochemistry (Paraffin)
• Clone: 4C4.9
• Dilution: Western Blot, ELISA, Immunohistochemistry-Paraffin
• Gene Alias: protein S100-A1, S100 alpha, S100 calcium binding protein A1, S100 calcium-binding protein A1S100, S-100 protein alpha chain, S-100 protein subunit alpha, S100 protein, alpha polypeptide, S100A, S100-alpha
• Host Species: Mouse
• Purification Method: Protein A or G purified
• Research Discipline: Alzheimers Research, Apoptosis, Biologically Active Proteins, Breast Cancer, Cancer, Cell Biology, Cellular Markers, Epigenetics, Hypoxia, Lipid and Metabolism, Neurodegeneration, Neuronal Cell Markers, Neuroscience, Peroxisome Markers, Signal Transduction, Stem Cells
• Gene ID (Entrez): 6271.0
• Target Species: Human, Mouse, Rat, Bovine
• Isotype: IgG2a κ