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S100A1 Mouse, Clone: SPM354, Novus Biologicals™
SDP

Catalog No. p-7105483 Shop All R&D Systems Products
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0.2 mg
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Catalog No. Quantity
NBP232994B 0.2 mg
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Catalog No. NBP232994B Supplier Novus Biologicals Supplier No. NBP2329940.2MG

Description

Mouse Monoclonal Antibody

S100A1 Monoclonal antibody specifically detects Antigen in Bovine, Human, Mouse, Rat samples. It is validated for Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blotting.

Specifications

Antigen S100A1
Applications Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone SPM354
Conjugate Unconjugated
Dilution Western Blot 0.5-1ug/ml, Flow Cytometry 0.5-1ug/million cells, Immunocytochemistry/Immunofluorescence 1-2ug/ml, Immunoprecipitation 0.5-1ug/500ug protein lysate, Immunohistochemistry-Paraffin 0.5-1.0ug/ml, Immunohistochemistry-Frozen 0.5-1.0ug/ml
Formulation PBS with 0.05% BSA. with 0.05% Sodium Azide
Gene Accession No. P23297
Gene Alias protein S100-A1, S100 alpha, S100 calcium binding protein A1, S100 calcium-binding protein A1S100, S-100 protein alpha chain, S-100 protein subunit alpha, S100 protein, alpha polypeptide, S100A, S100-alpha
Gene Symbols S100A1
Host Species Mouse
Immunogen Purified bovine brain S100 protein
Purification Method Protein A purified
Quantity 0.2 mg
Regulatory Status RUO
Research Discipline Astrocyte Markers, Breast Cancer, Cancer, Cell Biology, Cellular Markers, Cytoskeleton Markers, Hypoxia, Lipid and Metabolism, Neuronal Cell Markers, Neuroscience, Peroxisome Markers, Signal Transduction
Primary or Secondary Primary
Gene ID (Entrez) 6271
Test Specificity S100 belongs to the family of calcium binding proteins. S100A and S100B proteins are two members of the S100 family. S100A is composed of an alpha and beta chain whereas S100B is composed of two beta chains. S-100 protein has been found in normal melanocytes, Langerhans cells, histiocytes, chondrocytes, lipocytes, skeletal and cardiac muscle, Schwann cells, epithelial and myoepithelial cells of the breast, salivary and sweat glands, as well as in glial cells. Neoplasms derived from these cells also express S-100 protein, albeit non-uniformly. A large number of well-differentiated tumors of the salivary gland, adipose and cartilaginous tissue, and Schwann cell-derived tumors express S-100 protein. Almost all malignant melanomas and cases of histiocytosis X are positive for S-100 protein. Despite the fact that S-100 protein is an ubiquitous substance, its demonstration is of great value in the identification of several neoplasms, particularly melanomas and their metastases.
Target Species Human, Mouse, Rat, Bovine
Content And Storage Store at 4C.
Form Purified
Isotype IgG2a κ
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