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MilliporeSigma™ S100A4, Mouse, Unlabeled, Clone: 9D5.1,

Catalog No. MABC653MI Shop All MilliporeSigma Products
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Quantity:
100 μg
Conjugate:
Unconjugated
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Catalog No. Quantity Conjugate
MABC653MI 100 μg Unconjugated
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Catalog No. MABC653MI Supplier MilliporeSigma™ Supplier No. MABC653
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Description

Mouse Monoclonal Antibody

Protein S100-A4 (UniProt P26447; also known as Calvasculin, Metastasin, Placental calcium-binding protein, Protein Mts1, S100 calcium-binding protein A4) is encoded by the S100A4 (also known as CAPL, MTS1, P9KA, PEL98) gene (Gene ID 6275) in human. S100A4 belongs to a family of low moleclar weight proteins characterized by two calcium-binding helix-loop-helix EF-hand domains (a.a. 12-47 and 50-85 of human S100A4). S100 proteins exist as non-covalent homodimers with cell-specific expression patterns. S100A4 associates with cytoskeletal proteins, such as myosin and F-actin, as well as other actin-binding proteins such as Talin and integrins, and is involved in controlling not just shape and motility of normal cells, but also plays a role in cancer cells invasion/metastasis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen S100A4
Applications Western Blot
Classification Monoclonal
Clone 9D5.1
Concentration Please refer to lot specific datasheet.
Conjugate Unconjugated
Formulation Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene S100A4, CAPL, MTS1, P9KA, PEL98
Gene Accession No. P26447
Host Species Mouse
Immunogen GST-tagged recombinant human S100A4 internal fragment.
Purification Method Protein G Purified
Quantity 100 μg
Regulatory Status RUO
Research Discipline Apoptosis & Cancer
Primary or Secondary Primary
Gene ID (Entrez) NP_002952
Test Specificity Clone 9D5.1 was raised against human S100-A4 internal fragment that shares high sequence homology with the corresponding region in mouse (96%) and rat (93%) protein.
Target Species Human
Content And Storage Stable for 1 year at 2°-8°C from date of receipt.
Form Purified
Isotype IgG1 κ
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For Research Use Only. Not for use in diagnostic procedures.

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