S100A8/A9 Antibody (MAC387), Alexa Fluor™ 350, Novus Biologicals™

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NBP247667AF350

Catalog No. NB007128

Description

S100A8/A9 Monoclonal specifically detects S100A8/A9 in Human, Mouse, Rat, Porcine, Bovine, Canine, Equine, Feline, Guinea Pig, Goat, Baboon, Monkey, Rabbit samples. It is validated for Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunofluorescence.

Specifications

• Antigen: S100A8/A9
• Classification: Monoclonal
• Conjugate: Alexa Fluor 350
• Formulation: 50mM Sodium Borate with 0.05% Sodium Azide
• Gene Symbols: S100A8
• Immunogen: Affinity purified monocyte membrane preparation
• Quantity: 0.1 mL
• Research Discipline: Cancer
• Test Specificity: Recognizes the L1 or Calprotectin molecule, an intra-cytoplasmic antigen comprising of a 12kDa alpha chain and a 14kDa beta chain expressed by granulocytes, monocytes and by tissue macrophages. Macrophages usually arise from hematopoietic stem cells in the bone marrow. Under migration into tissues, the monocytes undergo further differentiation to become multifunctional tissue macrophages. They are classified into normal and inflammatory macrophages. Normal macrophages include macrophages in connective tissue (histiocytes), liver (Kupffers cell) and in other tissues. Inflammatory macrophages are present in various exudates. Macrophages are part of the innate immune system, recognizing, engulfing and destroying many potential pathogens including bacteria, pathogenic protozoa, fungi and helminthes. This monoclonal antibody reacts with neutrophils, monocytes, macrophages, and squamous mucosal epithelia and has been shown as an important marker for identifying macrophages in tissue sections.
• Content And Storage: Store at 4°C in the dark.

• Applications: Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence
• Clone: MAC387
• Dilution: Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence
• Gene Alias: 60B8AG, CAGA, CFAG, CGLA, CP-10, L1Ag, MA387, MIF, MRP8, NIF, P8, S100 calcium binding protein A8, S100A8
• Host Species: Mouse
• Purification Method: Protein A or G purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat, Pig, Canine, Equine, Feline, Guinea Pig, Goat, Baboon, Monkey, Rabbit
• Isotype: IgG1 κ