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S100A8/A9 Antibody (MAC387), Alexa Fluor™ 750, Novus Biologicals™
SDP

Catalog No. NB007131 Shop All R&D Systems Products
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NB007131 0.1 mL
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Catalog No. NB007131 Supplier Novus Biologicals Supplier No. NBP247667AF750
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Description

Mouse Monoclonal Antibody

S100A8/A9 Monoclonal specifically detects S100A8/A9 in Human, Mouse, Rat, Porcine, Bovine, Canine, Equine, Feline, Guinea Pig, Goat, Baboon, Monkey, Rabbit samples. It is validated for Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunofluorescence.

Specifications

Antigen S100A8/A9
Applications Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence
Classification Monoclonal
Clone MAC387
Conjugate Alexa Fluor 750
Dilution Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence
Formulation 50mM Sodium Borate with 0.05% Sodium Azide
Gene Alias 60B8AG, CAGA, CFAG, CGLA, CP-10, L1Ag, MA387, MIF, MRP8, NIF, P8, S100 calcium binding protein A8, S100A8
Gene Symbols S100A8
Host Species Mouse
Immunogen Affinity purified monocyte membrane preparation
Purification Method Protein A or G purified
Quantity 0.1 mL
Regulatory Status RUO
Research Discipline Cancer
Primary or Secondary Primary
Test Specificity Recognizes the L1 or Calprotectin molecule, an intra-cytoplasmic antigen comprising of a 12kDa alpha chain and a 14kDa beta chain expressed by granulocytes, monocytes and by tissue macrophages. Macrophages usually arise from hematopoietic stem cells in the bone marrow. Under migration into tissues, the monocytes undergo further differentiation to become multifunctional tissue macrophages. They are classified into normal and inflammatory macrophages. Normal macrophages include macrophages in connective tissue (histiocytes), liver (Kupffers cell) and in other tissues. Inflammatory macrophages are present in various exudates. Macrophages are part of the innate immune system, recognizing, engulfing and destroying many potential pathogens including bacteria, pathogenic protozoa, fungi and helminthes. This monoclonal antibody reacts with neutrophils, monocytes, macrophages, and squamous mucosal epithelia and has been shown as an important marker for identifying macrophages in tissue sections.
Target Species Human, Mouse, Rat, Pig, Canine, Equine, Feline, Guinea Pig, Goat, Baboon, Monkey, Rabbit
Content And Storage Store at 4°C in the dark.
Isotype IgG1 κ
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