S100A8 Monoclonal Antibody (CF-145), eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

Supplier:  LIFE TECHNOLOGIES 14974537

Catalog No. 14-974-537

Description

The MAb CF-145 recognizes human S100A8. S100A8, also known as migration inhibitory factor-related protein 8 (MRP-8) or Calgranulin-A, is a calcium binding protein and member of the S100 family of proteins. S100A8 is expressed by neutrophils, monocytes, macrophages, granulocytes, and epithelial cells during dermatoses, such as psoriasis. S100A8 forms a heterodimer with S100A9, which together is known as calprotectin. S100A8 has antimicrobial and pro-apoptotic properties and is a pro-inflammatory mediator in acute and chronic inflammation. Levels of S100A8 are elevated in patients with various inflammatory disorders such as cystic fibrosis, rheumatoid arthritis, and chronic bronchitis. Upregulation of S100A8 is also observed in many tumors, including skin, breast, colon, pancreatic, and ovarian cancers.

S100A8 Monoclonal antibody specifically detects S100A8 in Human samples. It is validated for Immunohistochemistry (Paraffin), Western Blot

Specifications

• Antigen: S100A8
• Classification: Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 0.09% sodium azide; pH 7.2
• Gene Accession No.: P05109
• Host Species: Mouse
• Quantity: 2 mg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b κ

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: CF-145
• Conjugate: Unconjugated
• Gene: S100A8
• Gene Alias: 60B8AG; AI323541; B8Ag; Caga; calgranulin A; calgranulin-A; Calprotectin L1L subunit; CFAG; CGLA; Chemotactic cytokine CP-10; chemotactic S100 protein; CP-10; Cystic fibrosis antigen; L1Ag; Leukocyte L1 complex light chain; MA387; MIF; Migration inhibitory factor-related protein 8; Mrp8; MRP-8; NIF; P8; pro-inflammatory S100 cytokine; Protein S100-A8; S100 A8; S100 calcium binding protein A8; S100 calcium binding protein A8 (calgranulin A); S100 calcium-binding protein A8; S100 calcium-binding protein A8 (calgranulin A); S100a8; Urinary stone protein band A
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 6279
• Content And Storage: 4° C
• Form: Liquid