S100B Monoclonal Antibody (OTI6C5), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA800495

Catalog No. 50-167-8371

Description

S100B is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells and are involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100B may function in neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several diseases, including Alzheimer′s disease, Down′s syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes.

Specifications

• Antigen: S100B
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: P04271
• Gene Symbols: S100B
• Immunogen: Full length human recombit protein of human S100B produced in HEK293T cell.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Western Blot
• Clone: OTI6C5
• Conjugate: Unconjugated
• Gene: S100B
• Gene Alias: NEF, S100, S100-B, S100beta
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 6285
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid