S100B Mouse anti-Human, Clone: OTI2H7, lyophilized, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene CF801095

Catalog No. 50-166-5448

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

S100B is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells and are involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100B may function in neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several diseases, including Alzheimer′s disease, Down′s syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes.

Specifications

• Antigen: S100B
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: S100B
• Gene Alias: NEF, S100, S100-B, S100beta
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 6285
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Western Blot
• Clone: OTI2H7
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: P04271
• Gene Symbols: S100B
• Immunogen: Full length human recombit protein of human S100B produced in E.coli.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1