S100B Mouse anti-Human, Clone: OTI3G6, lyophilized, TrueMAB
Mouse Monoclonal Antibody
Manufacturer: OriGene CF807235
Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCOS100B is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells and are involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100B may function in neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several diseases, including Alzheimer ft.s disease, Down ft.s syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes.
|Immunohistochemistry (Paraffin), Western Blot|
|PBS with 8% trehalose and no preservative; pH 7.3|
|NEF, S100, S100-B, S100beta|
|-20° C, Avoid Freeze/Thaw Cycles|
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