Invitrogen™ S100B Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA524996

Catalog No. PIPA524996

Description

This antibody is predicted to react with rabbit based on sequence homology.

S100B is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells and are involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100B may function in neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes.

Specifications

• Antigen: S100B
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: S100B
• Gene Alias: AI850290; Bpb; hypothetical protein LOC525716; NEF; protein S100-B; S100; S100 calcium binding protein B; S100 calcium binding protein beta (neural); S100 calcium-binding protein B; S100 calcium-binding protein beta (neural); S-100 calcium-binding protein beta subunit; S100 calcium-binding protein, beta (neural); S-100 calcium-binding protein, beta chain; S100 protein beta chain; S-100 protein beta chain; S-100 protein subunit beta; S100 protein, beta polypeptide; S100 protein, beta polypeptide, neural; S100B; S100-B; S100beta; S100P
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography, Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 20203, 25742, 6285
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.48 mg/mL
• Formulation: PBS with 0.09% sodium azide; pH 7.4
• Gene Accession No.: P04271, P04631, P50114
• Gene Symbols: S100B
• Immunogen: S100B recombinant protein.
• Quantity: 400 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov