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S1PR1/EDG1 Rabbit anti-Human, Mouse, Polyclonal, Proteintech
SDP

Catalog No. 501736007 Shop All Proteintech Group Inc Products
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50-173-6007 150 μL
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Catalog No. 50-173-6007 Supplier Proteintech Group Inc Supplier No. 551331AP150UL
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Description

Rabbit Polyclonal Antibody

The antibody is specific to S1PR1.

S1P1 is a G-protein coupled receptor for the bioactive lysosphingolipid sphingosine 1-phosphate (S1P) that is coupled to the G(i) subclass of heteromeric G proteins. S1P1 signaling leads to the activation of RAC1, SRC, PTK2/FAK1 and MAP kinases. It plays an important role in cell migration via its role in the reorganization of the actin cytoskeleton and formation of lamellipodia in response to stimuli that increase the activity of the sphingosine kinase SPHK1. S1P1 is required for normal chemotaxis toward sphingosine 1-phosphate, normal embryonic heart development, and normal cardiac morphogenesis.

Specifications

Antigen S1PR1/EDG1
Applications Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.77 mg/mL
Conjugate Unconjugated
Formulation 0.1 M glycine, 0.1 M sodium bicarbonate with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene S1PR1
Gene Accession No. O08530, P21453
Gene Alias CD363, CHEDG1, D1S3362, ECGF1, EDG 1, EDG1, S1P receptor 1, S1P receptor Edg 1, S1P1, S1PR1
Gene Symbols S1PR1
Host Species Rabbit
Immunogen Peptide
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 13609, 1901
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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