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Invitrogen™ SAA4 Polyclonal Antibody
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Catalog No. PIPA563819
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100 μL
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PIPA563819 100 μL
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Catalog No. PIPA563819 Supplier Invitrogen™ Supplier No. PA563819
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: FKEALQGVGD MGRAYWDIMI SNHQNSNRYL YARGNYDAA Highest antigen sequence identity to the following orthologs: Mouse - 59%, Rat - 59%.

Serum Amyloid A4 (SAA4) is a gene that encodes one of the constitutively expressed serum amyloid proteins. Located on chromosome 11, SAA4 is part of the serum amyloid A (SAA) superfamily, which includes other highly homologous genes like SAA1, SAA2, and SAA3. Unlike its counterparts, SAA4 is not an acute-phase reactant but is persistently expressed across different tissues, including plasma, where it associates with high-density lipoprotein (HDL). SAA4 is involved in lipid metabolism and inflammatory responses, albeit not directly induced by inflammatory stimuli like other SAA proteins. It appears as multiple isoforms, some of which may be glycosylated. Recent studies have shown that SAA4 expression encompasses a broad spectrum of physiological conditions and may serve as a marker in diseases involving chronic inflammation and persistent pathological states such as neovascular age-related macular degeneration. The gene's constitutive expression pattern suggests its fundamental role in maintaining homeostasis rather than responding dynamically to acute inflammatory challenges.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SAA4
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Saa4
Gene Accession No. P35542
Gene Alias amyloid A-5 protein; Constitutively expressed serum amyloid A protein; CSAA; C-SAA; Saa4; Saa-4; Saa5; Saa-5; serum amyloid A 4; serum amyloid A-4 protein; serum amyloid A4, constitutive
Gene Symbols Saa4
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human SAA4. Recombinant protein control fragment (Product #RP-100823).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6291
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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