Invitrogen™ SAE1 Recombinant Rabbit Monoclonal Antibody (0L2N2)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA542632

Catalog No. PIMA542632

Description

Positive test controls include: 293T, MCF7, DU145, Mouse testis, Mouse thymus, Rat testis. The target is usually found in the following locations: Nucleus. Immunogen sequence: DSSETTMVKK KVVFCPVKEA LEVDWSSEKA KAALKRTTSD YFLLQVLLKF RTDKGRDPSS DTYEEDSELL LQIRNDVLDS LGISPDLLPE DFVRYCFSEM A.

Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1), or sumoylation, regulates protein structure and intracellular localization. SAE1 and UBA2. form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins (Okuma et al., 1999).

Specifications

• Antigen: SAE1
• Classification: Recombinant Monoclonal
• Concentration: 0.6 mg/mL
• Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q6AXQ0, Q9R1T2, Q9UBE0
• Gene Symbols: SAE1
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 200-300 of human SAE1 (Q9UBE0).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA, Western Blot
• Clone: 0L2N2
• Conjugate: Unconjugated
• Gene: SAE1
• Gene Alias: 2400010M20Rik; 2610044L12Rik; activator of SUMO1; AL033372; AOS1; AW743391; D7Ertd177e; FLJ3091; HSPC140; Sae1; sentrin/SUMO-activating protein AOS1; Sua1; SUMO-1 activating enzyme E1 N subunit; SUMO1 activating enzyme subunit 1; SUMO-1 activating enzyme subunit 1; SUMO-activating enzyme subunit 1; SUMO-activating enzyme subunit 1, N-terminally processed; ubiquitin-like (sentrin) activating enzyme E1A; ubiquitin-like 1 (sentrin) activating enzyme E1A; ubiquitin-like 1 (sentrin) activating enzyme subunit 1; ubiquitin-like 1-activating enzyme E1A; ubiquitin-like protein SUMO-1 activating enzyme; Ubl1a1; Uble1a
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10055, 308384, 56459
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid