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Invitrogen™ SAE1 Recombinant Rabbit Monoclonal Antibody (0L2N2)
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Catalog No. PIMA542632
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PIMA542632 100 μL
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Catalog No. PIMA542632 Supplier Invitrogen™ Supplier No. MA542632
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Rabbit Recombinant Monoclonal Antibody

Positive test controls include: 293T, MCF7, DU145, Mouse testis, Mouse thymus, Rat testis. The target is usually found in the following locations: Nucleus. Immunogen sequence: DSSETTMVKK KVVFCPVKEA LEVDWSSEKA KAALKRTTSD YFLLQVLLKF RTDKGRDPSS DTYEEDSELL LQIRNDVLDS LGISPDLLPE DFVRYCFSEM A.

Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1), or sumoylation, regulates protein structure and intracellular localization. SAE1 and UBA2. form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins (Okuma et al., 1999).
TRUSTED_SUSTAINABILITY

Specifications

Antigen SAE1
Applications ELISA, Western Blot
Classification Recombinant Monoclonal
Clone 0L2N2
Concentration 0.6 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene SAE1
Gene Accession No. Q6AXQ0, Q9R1T2, Q9UBE0
Gene Alias 2400010M20Rik; 2610044L12Rik; activator of SUMO1; AL033372; AOS1; AW743391; D7Ertd177e; FLJ3091; HSPC140; Sae1; sentrin/SUMO-activating protein AOS1; Sua1; SUMO-1 activating enzyme E1 N subunit; SUMO1 activating enzyme subunit 1; SUMO-1 activating enzyme subunit 1; SUMO-activating enzyme subunit 1; SUMO-activating enzyme subunit 1, N-terminally processed; ubiquitin-like (sentrin) activating enzyme E1A; ubiquitin-like 1 (sentrin) activating enzyme E1A; ubiquitin-like 1 (sentrin) activating enzyme subunit 1; ubiquitin-like 1-activating enzyme E1A; ubiquitin-like protein SUMO-1 activating enzyme; Ubl1a1; Uble1a
Gene Symbols SAE1
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence within amino acids 200-300 of human SAE1 (Q9UBE0).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10055, 308384, 56459
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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