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R&D Systems™ SAK 3
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Catalog No. 62395 Shop All Novus Products
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Catalog No. Quantity
62-395 5 mg
62-392-5 25 mg
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Catalog No. 62-395 Supplier R&D Systems™ Supplier No. 6239/5

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Description

A Tocris product, part of R&D Systems. Potent CaV3.1/3.3 activator; orally bioavailable

SAK 3 is a potent CaV3.1 and CaV3.3 activator. Enhances CaV3.1 and CaV3.3, but not CaV3.2 activity at concentrations of 0.01 - 10 M in neuro2A cells in vitro. Elevates ACh levels in hippocampus. Rescues impaired memory-related behaviors, promotes adult neurogenesis and displays antidepressant-like effects in OBX mice. Orally bioavailable.

Specifications

Chemical Name or Material Ethyl 8′-methyl-2′,4-dioxo-2-(piperidin-1-yl)-2′H-spiro[cyclopent[2]ene-1,3′-imidazo[1,2-a]pyridine]-3-carboxylate
CAS 1256269-87-0
Quantity 5 mg
Product Line Tocris
Target Cav3.x Channel Activators
Molecular Formula C20H23N3O4
Purity 98%
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