Tocris Sal 003
Cell-permeable inhibitor of eIF2alpha dephosphorylation
Manufacturer: Tocris 3657/50
DescriptionCell-permeable inhibitor of cellular phosphatase complexes that dephosphorylate eukaryotic translation initiation factor 2 subunit α (eIF2α). Analog of salubrinal (Cat. No. 2347) with improved aqueous solubility. Shown to prevent the induction of hippocampal long-term potentiation (LTP) and memory formation (LTM) in mice.
- Chemical Name: 3--Phenyl-N-(2,2,2-trichloro-1-((((4-chlorophenyl)amino)carbonothioyl)amino)ethyl)acrylamide
- Formula: C18H15Cl4N3OS
- CAS Number: 1164470-53-4
- Solubility: Soluble to 100mM in DMSO
- Purity: >99
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