Tocris™ Sal 003

Cell-permeable inhibitor of eIF2alpha dephosphorylation

Manufacturer: Tocris™ 3657/50

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Catalog No. 36-575-0R

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For Research Use Only


    Inhibitors Sal 003
    Purity >99
    Molecular Weight 463.21
    Quantity 50mg
    Product Type Sal 003

    Cell-permeable inhibitor of cellular phosphatase complexes that dephosphorylate eukaryotic translation initiation factor 2 subunit α (eIF2α). Analog of salubrinal (Cat. No. 2347) with improved aqueous solubility. Shown to prevent the induction of hippocampal long-term potentiation (LTP) and memory formation (LTM) in mice.

    • Chemical Name: 3--Phenyl-N-(2,2,2-trichloro-1-((((4-chlorophenyl)amino)carbonothioyl)amino)ethyl)acrylamide
    • Formula: C18H15Cl4N3OS
    • CAS Number: 1164470-53-4
    • Solubility: Soluble to 100mM in DMSO
    • Purity: >99

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