Invitrogen™ SALL4 Monoclonal Antibody (A7A5)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA550591

Catalog No. FEMA550591

Description

Positive control: NCCIT cell lysates, human seminoma tissue. Predicted band size: 112 kDa Subcellular Location: Cytoplasm, Nucleus.

Sall4 protein is encoded by the Sall4 gene located on chromosome 20 in humans and belongs to the Spalt-like protein family. It plays an important role in somatic stem cell maintenance and is studied as a stem cell biomarker. It is a zinc finger transcription factor that is upregulated during development and shown to interact with Oct4 and Sox2. It also forms a complex with Nanog to maintain the pluripotency of Embryonic Stem cells (ESCs). Several current research studies focus on its function as an oncogene and tumor biomarker. Some of the reported target genes of Sall4 include p53, Bmi-1, Bcl2 and XIAP.

Specifications

• Antigen: SALL4
• Classification: Monoclonal
• Concentration: 2 mg/mL
• Formulation: PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: Q9UJQ4
• Gene Symbols: SALL4
• Immunogen: Recombinant protein within human Sall4 aa 903-1053/1053.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: A7A5
• Conjugate: Unconjugated
• Gene: SALL4
• Gene Alias: 5730441M18Rik; AA407717; AL022809; AW536104; C330011P20Rik; C78083; C78563; dJ1112F19.1; DRRS; HSAL4; SALL4; sal-like 4; sal-like 4 (Drosophila); sal-like protein 4; spalt like transcription factor 4; spalt-like transcription factor 4; Tex20; Zinc finger protein 797; zinc finger protein SALL4; ZNF797
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 57167
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid