Invitrogen™ SAMSN1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA582400

Catalog No. PIPA582400

Description

Immunogen sequence: TEAHEGDPTN GSGEQSKTSN NGGGLGKKMR AISWTMKKKV GKKYIKALSE EKDEEDGENA HPYRNSDPVI GTHTEKVSLK ASDSMDSLYS GQSSSSGITS CSDGTSNRDS FRLDDDGPYS GPFC.

SAMSN (HACS1) is a member of a novel gene family of putative adaptors and scaffold proteins containing SH3 and SAM (sterile alpha motif) domains. It encodes a 441 amino acid protein that is differentially expressed in hematopoietic cells and malignancies including myeloid leukemia, lymphoma, and myeloma. SAMSN has restricted expression in human tissues. It has been shown to be up-regulated by B cell activation signals and is a participant in B cell activation and differentiation. SAMSN is an immunoinhibitory adaptor that might be a useful target for immune suppression therapy.

Specifications

• Antigen: SAMSN1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SAMSN1
• Gene Alias: 4930571B16Rik; 930571B16Rik; HACS1; hematopoietic adapter-containing SH3 and sterile α-motif (SAM) domains 1; hematopoietic adapter-containing SH3 and sterile alpha-motif (SAM) domains 1; hematopoietic adaptor containing SH3 and SAM domains 1; Nash; NASH1; nuclear localization signals, SAM and SH3 domain containing 1; SAM and SH3 domain containing 2; SAM domain, SH3 domain and nuclear localisation signals, 1; SAM domain, SH3 domain and nuclear localization signals 1; SAM domain, SH3 domain and nuclear localization signals protein 1; SAM domain, SH3 domain and nuclear localization signals, 1; SAM domain-containing protein SAMSN-1; SAMSN; Samsn1; SAMSN-1; SASH2; SH3 protein expressed in lymphocytes 2; SH3D6B; SH3-lymphocyte protein 2; SH3-SAM adaptor protein; SLy2; Src homology domain 3 (SH3)-containing adapter protein SH3 lymphocyte protein 2
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 64092
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9NSI8
• Gene Symbols: SAMSN1
• Immunogen: Recombinant protein corresponding to Human SAMSN1. Recombinant protein control fragment (Product #RP-89850).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG