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Tocris Bioscience™ Sanguinarine chloride
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Catalog No. 23025
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25 mg
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23-025 5 mg
23-022-5 25 mg
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Catalog No. 23-025 Supplier Tocris Bioscience™ Supplier No. 2302/5
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Description

Inhibitor of protein phosphatase 2C (PP2C)

Sanguinarine chloride is an inhibitor of protein phosphatase 2C (PP2C), selective over PP1, PP2A and PP2B in vitro. Also inhibits mitogen-activated protein kinase phosphatase-1 (MKP-1) (IC50 = 10 μM). Plant alkaloid that exhibits anti-inflammatory and antioxidant activity. Blocks cell cycle in the G1 phase; inhibits cell growth in human prostate carcinoma cells.

Specifications

Chemical Name or Material 13-Methyl-[1,3]-benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridinium chloride
CAS 5578-73-4
Assay Percent Range >97%
Quantity 5 mg
Molecular Formula C20H14ClNO4
Formula Weight Observed MW: 367.78
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