Invitrogen™ SAP18 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA578314

Catalog No. PIPA578314

Description

Positive Control: K562, K562 nuclear extract Predicted Reactivity: Mouse (98%), Rat (98%), Zebrafish (90%), Xenopus laevis (87%), Dog (99%), Chicken (99%), Rhesus Monkey (100%), Bovine (99%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

SAP18 is involved in histone acetylation, which plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. The protein encoded by this gene is a component of the histone deacetylase complex, which includes SIN3, SAP30, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This protein directly interacts with SIN3 and enhances SIN3-mediated transcriptional repression when tethered to the promoter. A pseudogene has been identified on chromosome 2.

Specifications

• Antigen: SAP18
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SAP18
• Gene Alias: 18 kDa Sin3-associated polypeptide; 2HOR0202; C530046K05Rik; cell growth inhibiting protein 38; cell growth-inhibiting gene 38 protein; cell growth-inhibiting protein 38; D11Ertd539e; EMegR4; GIG38; histone deacetlyase complex subunit SAP18; histone deacetylase complex subunit SAP18; SAP18; SAP18P; Sin3A associated protein 18; Sin3A associated protein 18kDa; Sin3A-associated protein, 18kDa; Sin3-associated polypeptide 18; sin3-associated polypeptide p18; sin3-associated polypeptide, 18 kDa; sin3-associated polypeptide, 18kDa; sin3-associated polypeptide, p18; Sinbp1
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10284
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
• Gene Accession No.: O00422
• Gene Symbols: SAP18
• Immunogen: Recombinant protein encompassing a sequence within the center region of human SAP18. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG