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Invitrogen™ SAP18 Polyclonal Antibody
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Catalog No. PIPA592207
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100 μL
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PIPA592207 100 μL
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Catalog No. PIPA592207 Supplier Invitrogen™ Supplier No. PA592207
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: AVESRVTQEE IKKEPEKPID REKTCPLLLR VFTTNNGRHH RMDEFSRGNV PSSELQIYTW MDATLKELTS LVKEVYPEAR KKGTHFNFAI VFTDVKRPGY RVKEIGSTMS GRKGTDDSMT LQSQKFQIGD YLDIAITPPN RAPPPSGRMR PY; Positive Samples: SW480; Cellular Location: Cytoplasm, Nucleus, Nucleus speckle.

SAP18 is involved in histone acetylation, which plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. The protein encoded by this gene is a component of the histone deacetylase complex, which includes SIN3, SAP30, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This protein directly interacts with SIN3 and enhances SIN3-mediated transcriptional repression when tethered to the promoter. A pseudogene has been identified on chromosome 2.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SAP18
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.91 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene SAP18
Gene Accession No. O00422, O55128
Gene Alias 18 kDa Sin3-associated polypeptide; 2HOR0202; C530046K05Rik; cell growth inhibiting protein 38; cell growth-inhibiting gene 38 protein; cell growth-inhibiting protein 38; D11Ertd539e; EMegR4; GIG38; histone deacetlyase complex subunit SAP18; histone deacetylase complex subunit SAP18; SAP18; SAP18P; Sin3A associated protein 18; Sin3A associated protein 18kDa; Sin3A-associated protein, 18kDa; Sin3-associated polypeptide 18; sin3-associated polypeptide p18; sin3-associated polypeptide, 18 kDa; sin3-associated polypeptide, 18kDa; sin3-associated polypeptide, p18; Sinbp1
Gene Symbols SAP18
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 21-172 of human SAP18 (NP_0058612).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10284, 20220, 290284
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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