Invitrogen™ SAP30L Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA565525

Catalog No. PIPA565525

Description

Immunogen sequence: KETLAYFIYMV KSNKSRLDQK SEGGKQLE Highest antigen sequence identity to the following orthologs - mouse 93%, rat 90%.

A novel TGF- beta up-regulated mRNA species, the Sin3-associated protein 30-like, SAP30L has been identified. The predicted nuclear localization signal of SAP30L is sufficient for nuclear transport of the protein although mutating it does not completely remove SAP30L from the nuclei. By reason of its nuclear localization and close homology to SAP30 it is thought that SAP30L might have a role in recruiting the Sin3-histone deacetylase complex to specific co-repressor complexes in response to TGF-beta, leading to the silencing of proliferation-driving genes in the differentiating intestinal epithelial cells.

Specifications

• Antigen: SAP30L
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SAP30L
• Gene Alias: 2310079P12Rik; AF006998; DKFZp667L2214; FLJ11526; FLJ23595; FLJ36497; HCV non-structural protein 4A-transactivated protein 2; Histone deacetylase complex subunit SAP30L; L55; NS4ATP2; SAP30 like; SAP30L; SAP30-like; Sin3 corepressor complex subunit SAP30L; Sin3A associated protein p30-like; sin3A-associated protein p30-like protein; sin3-associated protein p30-like
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 79685
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9HAJ7
• Gene Symbols: SAP30L
• Immunogen: Recombinant Human SAP30L. Recombinant protein control fragment (Product #RP-104861).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov