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Invitrogen™ SAP30L Polyclonal Antibody
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Catalog No. PIPA5140017
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100 μL
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PIPA5140017 100 μL
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Catalog No. PIPA5140017 Supplier Invitrogen™ Supplier No. PA5140017
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Description

Rabbit Polyclonal Antibody

Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user. Immunogen sequence: MNGFSTEEDS REGPPAAPAA AAPGYGQSCC LIE Highest antigen sequence indentity to the following orthologs: Rat - 94%, Mouse - 94%.

A novel TGF- beta up-regulated mRNA species, the Sin3-associated protein 30-like, SAP30L has been identified. The predicted nuclear localization signal of SAP30L is sufficient for nuclear transport of the protein although mutating it does not completely remove SAP30L from the nuclei. By reason of its nuclear localization and close homology to SAP30 it is thought that SAP30L might have a role in recruiting the Sin3-histone deacetylase complex to specific co-repressor complexes in response to TGF-beta, leading to the silencing of proliferation-driving genes in the differentiating intestinal epithelial cells.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SAP30L
Applications Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene SAP30L
Gene Accession No. Q9HAJ7
Gene Alias 2310079P12Rik; AF006998; DKFZp667L2214; FLJ11526; FLJ23595; FLJ36497; HCV non-structural protein 4A-transactivated protein 2; Histone deacetylase complex subunit SAP30L; L55; NS4ATP2; SAP30 like; SAP30L; SAP30-like; Sin3 corepressor complex subunit SAP30L; Sin3A associated protein p30-like; sin3A-associated protein p30-like protein; sin3-associated protein p30-like
Gene Symbols SAP30L
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human SAP30L. Recombinant protein control fragment (Product #RP-109670).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 79685
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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