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Invitrogen™ SAPK4 Monoclonal Antibody (R.618.4)
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Catalog No. PIMA514994
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100 μL
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Catalog No. Quantity
PIMA514994 100 μL
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Catalog No. PIMA514994 Supplier Invitrogen™ Supplier No. MA514994
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Description

Rabbit Monoclonal Antibody

It is not recommended to aliquot this antibody. This antibody is not cross-reactive with other isoforms of p38 MAPK.

MAPK13 (p38 delta) is a serine/threonine kinase that transduces a variety of extracellular signals, including cytokine and environmental stress responses. MAPK13 also regulates the differentiation of keratinocytes. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases, or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of SAPK4 encoding distinct isoforms have been reported.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SAPK4
Applications Immunoprecipitation, Western Blot
Classification Monoclonal
Clone R.618.4
Conjugate Unconjugated
Formulation 0.01M HEPES with 100μg/mL BSA, 50% glycerol, 0.15M NaCl and <0.02% sodium azide; pH 7.5
Gene MAPK13
Gene Accession No. O15264, Q9WTY9
Gene Alias im:7136778; MAP kinase 13; MAP kinase p38 delta; MAPK 13; Mapk13; MAPK-13; mitogen activated protein kinase 13; mitogen-activated protein kinase 13; Mitogen-activated protein kinase p38 delta; p38 delta MAP kinase; p38delta; PRKM13; SAPK/Erk/kinase 4; SAPK4; Serk4; Stress-activated protein kinase 4
Gene Symbols MAPK13
Host Species Rabbit
Immunogen Synthetic peptide corresponding to residues around the carboxy terminus of p38d MAPK.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 29513, 5603
Target Species Human, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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