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Invitrogen™ SAPK4 Polyclonal Antibody
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Catalog No. PA550553
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100 μL
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PA550553 100 μL
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Catalog No. PA550553 Supplier Invitrogen™ Supplier No. PA550553
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Description

Rabbit Polyclonal Antibody

The antibody detects endogenous levels of total MAPK13 protein.

MAPK13 (p38 delta) is a serine/threonine kinase that transduces a variety of extracellular signals, including cytokine and environmental stress responses. MAPK13 also regulates the differentiation of keratinocytes. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases, or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of SAPK4 encoding distinct isoforms have been reported.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SAPK4
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1.3 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
Gene MAPK13
Gene Accession No. O15264, Q9WTY9, Q9Z1B7
Gene Alias im:7136778; MAP kinase 13; MAP kinase p38 delta; MAPK 13; Mapk13; MAPK-13; mitogen activated protein kinase 13; mitogen-activated protein kinase 13; Mitogen-activated protein kinase p38 delta; p38 delta MAP kinase; p38delta; PRKM13; SAPK/Erk/kinase 4; SAPK4; Serk4; Stress-activated protein kinase 4
Gene Symbols MAPK13
Host Species Rabbit
Immunogen Synthetic peptide corresponding to residues near the C terminal of human mitogen-activated protein kinase 13.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 26415, 29513, 5603
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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