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Invitrogen™ SARS/SARS-CoV-2 Nucleocapsid Recombinant Rabbit Monoclonal Antibody (001)
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Catalog No. PIMA529982
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100 μL
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PIMA529982 100 μL
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Catalog No. PIMA529982 Supplier Invitrogen™ Supplier No. MA529982
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Description

Rabbit Recombinant Monoclonal Antibody

MA5-29982 cross reacts with SARS-CoV-2 (COVID-19) Nucleoprotein in ELISA and WB. This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%). Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire. This antibody has specificity for Human SARS Coronavirus Nucleoprotein/NP.

SARS-CoV-2 Nucleocapsid Protein is associated with nucleic acid. It is the most abundant protein for coronavirus. Because of the strong immunogenicity of coronavirus Nucleocapsid, it is believed that SARS-CoV-2 Nucleocapsid Protein has potential value for the diagnosis of the virus. The SARS-CoV-2 N protein is an abundant RNA-binding protein critical for viral genome packaging, yet the molecular details that involve this process are poorly understood. N protein contains three dynamic disordered regions that house putative transiently-helical binding motifs. The two folded domains interact minimally such that full-length N protein is a flexible and multivalent RNA-binding protein. SARS-CoV-2 causes illnesses ranging from the common cold to severe diseases.
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Specifications

Antigen SARS/SARS-CoV-2 Nucleocapsid
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone 001
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative
Gene N
Gene Accession No. P0DTC9
Gene Alias COVID19 Nucleocapsid; COVID-19 nucleocapsid; COVID19 Spike nucleocapsid; SARS-CoV-2 N
Gene Symbols N
Host Species Rabbit
Immunogen Recombinant Human SARS Coronavirus Nucleoprotein/NP Protein.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 43740575
Target Species Virus
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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