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Invitrogen™ SARS Coronavirus Spike Protein Polyclonal Antibody
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Catalog No. 01675739
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100 μg
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Catalog No. Quantity
01-675-739 100 μg
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Catalog No. 01-675-739 Supplier Invitrogen™ Supplier No. PA141165
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Description

Rabbit Polyclonal Antibody

This antibody has been used for Flow Cytometry to detect HEK293T.17 cells transfected with vaccine-expressing membrane-bound SARS-CoV-2 spike protein. View Article The immunogen is 100% (16/16) homologous to SARS-COV-2 (COVID-19) Spike protein. The cross reactivity is not empirically tested. Suggested positive control: transfected mouse melanoma cell lysate. Immunogen sequence: GNCDVVIGIV NNTVYDP.

It has recently been shown that SARS (severe acute respiratory syndrome) is caused by a human coronavirus. Human coronaviruses are the major cause of upper respiratory tract illness, such as the common cold, in humans. Coronaviruses are positive-stranded RNA viruses, featuring the largest viral RNA genomes known to date (27-31 kb). The first step in coronavirus infection is binding of the viral spike protein, a 139-kDa protein, to certain receptors on host cells. The spike protein is the main surface antigen of the coronavirus. The glycosylated spike protein (as well as the nucleocapsid protein) can be detected in infected cell culture supernatants with antisera from SARS patients.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SARS Coronavirus Spike Protein
Applications Western Blot
Classification Polyclonal
Concentration 1.0 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene Alias Coronavirus; COVID; Covid 19; COVID19; COVID-19; SARS; SARS Coronavirus; SARS CoV; SARS CoV2; SARS CoV-2; SARS Spike Protein; SARS-CoV2; SARS-CoV-2
Host Species Rabbit
Immunogen Synthetic peptide corresponding to amino acids 1124-1140 from the S (Spike glycoprotein) (Spike protein S2') for the Human SARS coronavirus.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Virus
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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