Invitrogen™ SARS-CoV-2 Nucleocapsid (AY.1; AY.3) His-tag Recombinant Protein

Description

Recombinant Protein

It is recommended that the protein be aliquoted for optimal storage. The mutations were identified in the SARS-CoV-2 varient known as AY.1 or AY.3

SARS-CoV-2 Nucleocapsid Protein is associated with nucleic acid. It is the most abundant protein for coronavirus. Because of the strong immunogenicity of coronavirus Nucleocapsid, it is believed that SARS-CoV-2 Nucleocapsid Protein has potential value for the diagnosis of the virus. The SARS-CoV-2 N protein is an abundant RNA-binding protein critical for viral genome packaging, yet the molecular details that involve this process are poorly understood. N protein contains three dynamic disordered regions that house putative transiently-helical binding motifs. The two folded domains interact minimally such that full-length N protein is a flexible and multivalent RNA-binding protein. SARS-CoV-2 causes illnesses ranging from the common cold to severe diseases.

Specifications

• Accession Number: P0DTC9
• For Use With (Application): Control
• Format: Lyophilized
• Formulation: PBS with 0.01% mannitol, 0.01% Tween 80, 5-8% trehalose and no preservative; pH 7.4
• Gene ID (Entrez): 43740575
• Molecular Weight (g/mol): 46.6 kDa
• Name: SARS-CoV-2 Nucleocapsid (AY0.1; AY0.3) His-tag
• Purification Method: SDS-PAGE
• Quantity: 100 μg
• Regulatory Status: RUO
• Gene Alias: COVID19 Nucleocapsid; COVID-19 nucleocapsid; COVID19 Spike nucleocapsid; SARS-CoV-2 N
• Common Name: SARS-CoV-2 Nucleocapsid
• Gene Symbol: N
• Product Type: Protein
• Conjugate: Unconjugated
• Recombinant: Recombinant
• Protein Tag: His-tag
• Sequence: SARS-CoV-2 nucleocapsid (Accession # YP_009724397.2), amino acids Met1-Ala419 with D63G, R203M, G215C, D377Y substitutions and an N-terminal His-tag
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Expression System: E. coli
• Form: Lyophilized
• Purity or Quality Grade: >95% as determined by SDS-PAGE.