Invitrogen™ SARS-CoV-2 Nucleocapsid Recombinant Human Monoclonal Antibody (RMH03)

Human Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA538681

Catalog No. PIMA538681

Description

This antibody is a Human-Rabbit chimeric antibody, made by fusion of the antigen binding region (variable domains of the heavy and light chains, VH and VL) of a rabbit anti-NP (2019-nCov) monoclonal antibody, with the constant domain of Human IgG1. This antibody is recognized only by an anti-Human IgG secondary antibody.

SARS-CoV-2 Nucleocapsid Protein is associated with nucleic acid. It is the most abundant protein for coronavirus. Because of the strong immunogenicity of coronavirus Nucleocapsid, it is believed that SARS-CoV-2 Nucleocapsid Protein has potential value for the diagnosis of the virus. The SARS-CoV-2 N protein is an abundant RNA-binding protein critical for viral genome packaging, yet the molecular details that involve this process are poorly understood. N protein contains three dynamic disordered regions that house putative transiently-helical binding motifs. The two folded domains interact minimally such that full-length N protein is a flexible and multivalent RNA-binding protein. SARS-CoV-2 causes illnesses ranging from the common cold to severe diseases.

Specifications

• Antigen: SARS-CoV-2 Nucleocapsid
• Classification: Recombinant Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide
• Gene Accession No.: P0DTC9
• Gene Symbols: N
• Immunogen: A recombinant 2019-nCov Nucleocapsid Protein expressed in E. coli.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Virus
• Product Type: Antibody
• Isotype: IgG1

• Applications: ELISA
• Clone: RMH03
• Conjugate: Unconjugated
• Gene: N
• Gene Alias: COVID19 Nucleocapsid; COVID-19 nucleocapsid; COVID19 Spike nucleocapsid; SARS-CoV-2 N
• Host Species: Human
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 43740575
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid