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Invitrogen™ SARS-CoV-2 Nucleocapsid Recombinant Human Monoclonal Antibody (RMH03)
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Catalog No. PIMA538681
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100 μg
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PIMA538681 100 μg
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Catalog No. PIMA538681 Supplier Invitrogen™ Supplier No. MA538681
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Description

Human Recombinant Monoclonal Antibody

This antibody is a Human-Rabbit chimeric antibody, made by fusion of the antigen binding region (variable domains of the heavy and light chains, VH and VL) of a rabbit anti-NP (2019-nCov) monoclonal antibody, with the constant domain of Human IgG1. This antibody is recognized only by an anti-Human IgG secondary antibody.

SARS-CoV-2 Nucleocapsid Protein is associated with nucleic acid. It is the most abundant protein for coronavirus. Because of the strong immunogenicity of coronavirus Nucleocapsid, it is believed that SARS-CoV-2 Nucleocapsid Protein has potential value for the diagnosis of the virus. The SARS-CoV-2 N protein is an abundant RNA-binding protein critical for viral genome packaging, yet the molecular details that involve this process are poorly understood. N protein contains three dynamic disordered regions that house putative transiently-helical binding motifs. The two folded domains interact minimally such that full-length N protein is a flexible and multivalent RNA-binding protein. SARS-CoV-2 causes illnesses ranging from the common cold to severe diseases.
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Specifications

Antigen SARS-CoV-2 Nucleocapsid
Applications ELISA
Classification Recombinant Monoclonal
Clone RMH03
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide
Gene N
Gene Accession No. P0DTC9
Gene Alias COVID19 Nucleocapsid; COVID-19 nucleocapsid; COVID19 Spike nucleocapsid; SARS-CoV-2 N
Gene Symbols N
Host Species Human
Immunogen A recombinant 2019-nCov Nucleocapsid Protein expressed in E. coli.
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 43740575
Target Species Virus
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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