Invitrogen™ SARS-CoV-2 ORF9b Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5116951

Catalog No. PIPA5116951

Description

Positive Samples: 293T Immunogen sequence: MDPKISEMHP ALRLVDPQIQ LAVTRMENAV GRDQNNVGPK VYPIILRLGS PLSLNMARKT LNSLEDKAFQ LTPIAVQMTK LATTEELPDE FVVVTVK.

ORF9b plays a role in the inhibition of host innate immune response by targeting the mitochondrial-associated adapter MAVS. Mechanistically, usurps the E3 ligase ITCH to trigger the degradation of MAVS, TRAF3, and TRAF6. In addition, causes mitochondrial elongation by triggering ubiquitination and proteasomal degradation of dynamin-like protein 1/DNM1L.

Specifications

• Antigen: SARS-CoV-2 ORF9b
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene Alias: COVID19 ORF9b; COVID-19 ORF9b; ORF9b; SARS-CoV-2 Open Reading Frame 9b; SARS-COV2 ORF9b
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-97 of coronavirus ORF9b (P0DTD2).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 1.55 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Target Species: Virus
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov