Invitrogen™ SARS-CoV-2 Spike (N501Y Mutant) Recombinant Rabbit Monoclonal Antibody (1J5G2)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA551234

Catalog No. FEMA551234

Description

Immunogen sequence: NYLYRLFRKS NLKPFERDIS TEIYQAGSTP CNGVEGFNCY FPLQSYGFQP TYGVGYQPYR VVVLSFELLH APATVCGPKK STNLVKNKCV NFNFNGLTGT G.

The spike protein in SARS-CoV-2 (SARS-2-S) interacts with the human ACE2 receptor to gain entry into a cell to initiate infection SARS-2-S is cleaved into S1 and S2 subunits, with S1 serving the function of receptor-binding and S2 serving the function of membrane fusion The S protein undergoes two crucial cleavage events, with the first splitting S1 and S2 and the second splitting S2 into FP and S2' [PMID: 33466921].

Specifications

• Antigen: SARS-CoV-2 Spike (N501Y Mutant)
• Classification: Recombinant Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 0.05% BSA, 50% glycerol and 0.05% ProClin 300; pH 7.3
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Target Species: Virus
• Product Type: Antibody
• Format: Liquid

• Applications: ELISA, Western Blot
• Clone: 1J5G2
• Conjugate: Unconjugated
• Gene Alias: 2019-nCoV Spike; COVID-19 Spike; SARS-CoV-2 Spike
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 450-550 of coronavirus SARS-CoV-2 Spike RBD (N501Y) (YP_009724390.1).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid
• Isotype: IgG