Invitrogen™ SARS-CoV-2 Spike Protein RBD Monoclonal Antibody (2G1)

Mouse Monoclonal Antibody

Catalog Number	Mfr. No.	Quantity
PIMA547307	Invitrogen™ MA547307	500 μL
PIMA547405	Invitrogen™ MA547405	100 μL

Description

SARS-CoV-2 Spike Protein RBD Monoclonal Antibody for Western Blot, ICC/IF

SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) also known as 2019-nCoV (2019 Novel Coronavirus) is a virus that causes illnesses ranging from the common cold symptoms to severe effects including death and respiratory distress. The CoV Spike (S) protein plays the most important roles in viral attachment, fusion and entry, and serves as a target for development of antibodies, entry inhibitors and vaccines. Of note is the Spike protein receptor-binding domain (RBD, S-RBD) in SARS-CoV-2 Spike protein which binds strongly to human and bat angiotensin-converting enzyme 2 (ACE2) receptors. SARS-CoV-2 RBD exhibits significantly higher binding affinity to ACE2 receptor than SARS-CoV RBD in comparison. S1 contains a receptor-binding domain (RBD) that can specifically bind to angiotensin-converting enzyme 2 (ACE2), the receptor on target cells.

Specifications

• Antigen: SARS-CoV-2 Spike Protein RBD
• Concentration: 1 mg/mL
• Applications: Western Blot, Immunocytochemistry
• Conjugate: Unconjugated
• Host Species: Mouse
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 5mM sodium azide
• Immunogen: Recombinant SARS-CoV2 S-Protein ACE2 binding domain expressed in and purified from E. coli.
• Product Type: Antibody

• Clone: 2G1
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Classification: Monoclonal
• Form: Liquid
• Isotype: IgG1
• Target Species: Virus
• Gene Alias: Coronavirus; COVID; Covid 19; COVID19; COVID-19; SARS; SARS Coronavirus; SARS CoV; SARS CoV2; SARS CoV-2; SARS Spike Protein; SARS-CoV2; SARS-CoV-2
• Primary or Secondary: Primary
• Purification Method: Protein A/G