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Invitrogen™ SARS-CoV-2 Spike Protein RBD Monoclonal Antibody (5G8)

Catalog No. PIMA547350
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500 μL
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PIMA547350 500 μL
PIMA547449 100 μL
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Catalog No. PIMA547350 Supplier Invitrogen™ Supplier No. MA547350
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Description

Mouse Monoclonal Antibody

SARS-CoV-2 Spike Protein RBD Monoclonal Antibody for Western Blot, ICC/IF, IHC

SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) also known as 2019-nCoV (2019 Novel Coronavirus) is a virus that causes illnesses ranging from the common cold symptoms to severe effects including death and respiratory distress. The CoV Spike (S) protein plays the most important roles in viral attachment, fusion and entry, and serves as a target for development of antibodies, entry inhibitors and vaccines. Of note is the Spike protein receptor-binding domain (RBD, S-RBD) in SARS-CoV-2 Spike protein which binds strongly to human and bat angiotensin-converting enzyme 2 (ACE2) receptors. SARS-CoV-2 RBD exhibits significantly higher binding affinity to ACE2 receptor than SARS-CoV RBD in comparison. S1 contains a receptor-binding domain (RBD) that can specifically bind to angiotensin-converting enzyme 2 (ACE2), the receptor on target cells.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SARS-CoV-2 Spike Protein RBD
Applications Immunohistochemistry, Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 5G8
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 5mM sodium azide
Gene Alias Coronavirus; COVID; Covid 19; COVID19; COVID-19; SARS; SARS Coronavirus; SARS CoV; SARS CoV2; SARS CoV-2; SARS Spike Protein; SARS-CoV2; SARS-CoV-2
Host Species Mouse
Immunogen Recombinant SARS-CoV2 S-Protein ACE2 binding domain expressed in and purified from E. coli.
Purification Method Protein A/G
Quantity 500 μL
Regulatory Status RUO
Primary or Secondary Primary
Target Species Virus
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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