Invitrogen™ SARS-CoV-2 Spike Protein RBD Recombinant Llama Monoclonal Antibody (1H12)

Catalog No.	Quantity
PIMA549347	100 μg

Catalog No. PIMA549347 Supplier Invitrogen™ Supplier No. MA549347

Description

Llama Recombinant Monoclonal Antibody

SARS-CoV-2 Spike Protein RBD Recombinant Monoclonal Antibody for ELISA, Neu

SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) also known as 2019-nCoV (2019 Novel Coronavirus) is a virus that causes illnesses ranging from the common cold symptoms to severe effects including death and respiratory distress. The CoV Spike (S) protein plays the most important roles in viral attachment, fusion and entry, and serves as a target for development of antibodies, entry inhibitors and vaccines. Of note is the Spike protein receptor-binding domain (RBD, S-RBD) in SARS-CoV-2 Spike protein which binds strongly to human and bat angiotensin-converting enzyme 2 (ACE2) receptors. SARS-CoV-2 RBD exhibits significantly higher binding affinity to ACE2 receptor than SARS-CoV RBD in comparison. S1 contains a receptor-binding domain (RBD) that can specifically bind to angiotensin-converting enzyme 2 (ACE2), the receptor on target cells.

Specifications

• Antigen: SARS-CoV-2 Spike Protein RBD
• Applications: ELISA, Neutralization
• Classification: Recombinant Monoclonal
• Clone: 1H12
• Conjugate: Unconjugated
• Formulation: PBS with no preservative
• Gene Alias: Coronavirus; COVID; Covid 19; COVID19; COVID-19; SARS; SARS Coronavirus; SARS CoV; SARS CoV2; SARS CoV-2; SARS Spike Protein; SARS-CoV2; SARS-CoV-2
• Host Species: Llama
• Immunogen: SARS-CoV-2 S protein RBD containing C-terminal His Tag. The protein was expressed in human 293 cells (HEK293). It contains amino acids Arg 319-Lys 537.
• Purification Method: Affinity chromatography
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Target Species: Virus
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: scFv