Invitrogen™ SARS-CoV-2 Spike Protein S1 Chimeric Recombinant Human Monoclonal Antibody (H6)

Human Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA535940

Catalog No. PIMA535940

Description

Recombinant anti-SARS-CoV-2 spike is expressed from 293 cells (HEK293). It is a chimeric monoclonal antibody combining the mouse variable regions with the constant domains of human IgG1. Compatible for use in Colloidal Gold Immunochromatography.

SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) also known as 2019-nCoV (2019 Novel Coronavirus) is a virus that causes illnesses ranging from the common cold symptoms to severe effects including death and respiratory distress. SARS-CoV-2 Spike Protein is composed of S1 domain and S2 domain (Spike Protein). The Spike protein is the main surface antigen of the coronavirus. The glycosylated Spike protein (as well as the nucleocapsid protein) can be detected in infected cell culture supernatants with antisera from SARS patients. S1 contains a receptor-binding domain (RBD) that can specifically bind to angiotensin-converting enzyme 2 (ACE2), the receptor on target cells. CoV diversity is reflected in the variable Spike proteins (S proteins), which have evolved into forms differing in their receptor interactions and their response to various environmental triggers of virus-cell membrane fusion.

Specifications

• Antigen: SARS-CoV-2 Spike Protein S1 Chimeric
• Classification: Recombinant Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
• Host Species: Human
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Target Species: Virus
• Product Type: Antibody
• Isotype: IgG1 κ

• Applications: ELISA, Lateral Flow
• Clone: H6
• Conjugate: Unconjugated
• Gene Alias: Coronavirus; COVID; Covid 19; COVID19; COVID-19; SARS; SARS Coronavirus; SARS CoV; SARS CoV2; SARS CoV-2; SARS Spike Protein; SARS-CoV2; SARS-CoV-2
• Immunogen: Recombinant Human Novel Coronavirus Spike glycoprotein (S) (16-685aa).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Content And Storage: -20°C or -80°C if preferred
• Form: Liquid