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Invitrogen™ SARS-CoV-2 Spike Protein S2/S2' (strain Wuhan-Hu-1) Polyclonal Antibody
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Catalog No. PIPA5143458
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100 μL
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PIPA5143458 100 μL
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Catalog No. PIPA5143458 Supplier Invitrogen™ Supplier No. PA5143458
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Description

Rabbit Polyclonal Antibody

Store as concentrated solution. Centrifuge briefly prior to opening vial.

The spike protein in SARS-CoV-2 (SARS-2-S) interacts with the human ACE2 receptor to gain entry into a cell to initiate infection SARS-2-S is cleaved into S1 and S2 subunits, with S1 serving the function of receptor-binding and S2 serving the function of membrane fusion The S protein undergoes two crucial cleavage events, with the first splitting S1 and S2 and the second splitting S2 into FP and S2' [PMID: 33466921].
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Specifications

Antigen SARS-CoV-2 Spike Protein S2/S2' (strain Wuhan-Hu-1)
Applications ELISA, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 20% glycerol and 0.025% Proclin 300; pH 7
Gene Alias 2019-nCoV Spike; COVID-19 Spike; SARS-CoV-2 Spike
Host Species Rabbit
Immunogen Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of SARS-CoV-2 Spike (S2). (SARS-CoV-2 (strain Wuhan-Hu-1)). The exact sequence is proprietary.
Purification Method Antigen Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Target Species Virus
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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