Invitrogen™ SARS-CoV Spike Protein RBD Polyclonal Antibody

Catalog No.	Quantity
PIPA5120762	100 μL

Catalog No. PIPA5120762 Supplier Invitrogen™ Supplier No. PA5120762

Description

Rabbit Polyclonal Antibody

Positive test controls include: 293T. Immunogen sequence: ADYSVLYNST FFSTFKCYGV SATKLNDLCF SNVYADSFVV KGDDVRQIAP GQTGVIADYN YKLPDDFMGC VLAWNTRNID ATSTGNYNYK YRYLRHGKLR P.

SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) also known as 2019-nCoV (2019 Novel Coronavirus) is a virus that causes illnesses ranging from the common cold symptoms to severe effects including death and respiratory distress. The CoV Spike (S) protein plays the most important roles in viral attachment, fusion and entry, and serves as a target for development of antibodies, entry inhibitors and vaccines. Of note is the Spike protein receptor-binding domain (RBD, S-RBD) in SARS-CoV-2 Spike protein which binds strongly to human and bat angiotensin-converting enzyme 2 (ACE2) receptors. SARS-CoV-2 RBD exhibits significantly higher binding affinity to ACE2 receptor than SARS-CoV RBD in comparison. S1 contains a receptor-binding domain (RBD) that can specifically bind to angiotensin-converting enzyme 2 (ACE2), the receptor on target cells.

Specifications

• Antigen: SARS-CoV Spike Protein RBD
• Applications: ELISA, Western Blot
• Classification: Polyclonal
• Concentration: 1.15 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
• Gene Alias: CoV; RBD; SARS; Spike
• Host Species: Rabbit
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 350-450 of coronavirus Spike RBD (NP_8288511).
• Purification Method: Affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Target Species: Virus
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG