Invitrogen™ SARS2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5110341

Catalog No. PIPA5110341

Description

Immunogen sequence: ARFKDLNLAG TAEVGLAGYF MDHTVAFRDL PVRMVCSSTC YRAETNTGQE PRGLYRVHHF TKVEMFGVTG PGLEQSSQLL EEFLSLQMEI LTELGLHFRV LDMPTQELGL PAYRKFDIEA WMPGRGRFGE VTSASNCTDF QSRRLHIMFQ TEAGELQFAH TVNATACAVP RLLIALLESN QQKDGSVLVP PALQSYLGTD RITAPTHVPL QYIGPNQPRK PGLPGQPAVS.

This gene encodes the mitochondrial seryl-tRNA synthetase precursor, a member of the class II tRNA synthetase family. The mature enzyme catalyzes the ligation of Serine to tRNA(Ser) and participates in the biosynthesis of selenocysteinyl-tRNA(sec) in mitochondria. The enzyme contains an N-terminal tRNA binding domain and a core catalytic domain. It functions in a homodimeric form, which is stabilized by tRNA binding. This gene is regulated by a bidirectional promoter that also controls the expression of mitochondrial ribosomal protein S12. Both genes are within the critical interval for the autosomal dominant deafness locus DFNA4 and might be linked to this disease. Multiple transcript variants encoding different isoforms have been identified for this gene.

Specifications

• Antigen: SARS2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SARS2
• Gene Alias: 2410015F05Rik; D7Ertd353e; EC 6.1.1.11; mitochondrial seryl-tRNA synthetase; mtSerRS; SARS; Sars2; Sarsm; serine tRNA ligase 2, mitochondrial; serine-tRNA ligase; serine-tRNA ligase, mitochondrial; serine--tRNA ligase, mitochondrial; SerRS; SerRS2; SerRSmt; SERS; seryl-aminoacyl-tRNA synthetase 2; Seryl-tRNA synthetase; seryl-tRNA synthetase 2; seryl-tRNA synthetase 2, mitochondrial; seryl-tRNA synthetase, mitochondrial; seryl-tRNA(Ser/Sec) synthetase; SYS; zgc:66345
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 54938, 71984
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.046 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: Q9JJL8, Q9NP81
• Gene Symbols: SARS2
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 289-518 of human SARS2 (NP_060297.1).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG