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Invitrogen™ SART3 Polyclonal Antibody
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Catalog No. PIPA588362
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100 μL
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PIPA588362 100 μL
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Catalog No. PIPA588362 Supplier Invitrogen™ Supplier No. PA588362
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: AGPAGKCAAV DVEPPSKQKE KAASLKRDMP KVLHDSSKDS ITVFVSNLPY SMQEPDTKLR PLFEACGEVV QIRPIFSNRG DFRGYCYVEF KEEKSALQAL EMDRKSVEGR PMFVSPCVDK SKNPDFKVFR YSTSLEKHKL FISGLPFSCT KEELEEICKA HGTVKDLRLV TNRAGKPKGL AYVEYENESQ ASQAVMKMDG MTIKENIIKV AISNPPQRKV PEKPETRKAP GGPMLLPQTY GARGKGRTQL SLLPRALQRP SAAAPQAENG PAAAPAVAAP AATEAPKMSN ADFAKLFLRK; Positive Samples: U-87MG, A-431, HeLa, HepG2, Jurkat; Cellular Location: Cajal body, Cytoplasm, Nucleus, Nucleus speckle, nucleoplasm.

The protein encoded by this gene is an RNA-binding nuclear protein that is a tumor-rejection antigen. This antigen possesses tumor epitopes capable of inducing HLA-A24-restricted and tumor-specific cytotoxic T lymphocytes in cancer patients and may be useful for specific immunotherapy. This gene product is found to be an important cellular factor for HIV-1 gene expression and viral replication. It also associates transiently with U6 and U4/U6 snRNPs during the recycling phase of the spliceosome cycle. This encoded protein is thought to be involved in the regulation of mRNA splicing.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SART3
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.42 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene SART3
Gene Accession No. Q15020, Q9JLI8
Gene Alias AU045857; DSAP1; HIV-1 Tat-interacting protein of 110kDa; hSART-3; Kiaa0156; MGC138188; mKIAA0156; mSART-3; P100; p110; p110 nuclear RNA-binding protein; p110(nrb); RP11-13G14; Sart3; SART-3; spliceosome associated factor 3, U4/U6 recycling protein; squamous cell carcinoma antigen recognised by T cells 3; squamous cell carcinoma antigen recognized by T cells 3; squamous cell carcinoma antigen recognized by T-cells 3; Tat-interacting protein of 110 kDa; Tip110; Tumor-rejection antigen SART3
Gene Symbols SART3
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 664-963 of human SART3 (NP_0555211).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 304582, 53890, 9733
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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