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Tocris Bioscience™ SB 203580 hydrochloride
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Catalog No. 140210
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10 mg
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Catalog No. Quantity
14-021-0 10 mg
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Catalog No. 14-021-0 Supplier Tocris Bioscience™ Supplier No. 1402/10
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Description

Selective inhibitor of p38 MAPK; water-soluble

Water-soluble salt of SB 203580 (Cat. No. 1202). Selective inhibitor of p38 mitogen-activated protein kinase (IC50 values are 50 and 500 nM for SAPK2a/p38 and SAPK2b/p38β2 respectively). Displays 100-500-fold selectivity over LCK, GSK3β and PKBα. Shown to inhibit interleukin-2-induced T cell proliferation, cyclooxygenase-1 and -2, and thromboxane synthase.

Chemical Identifiers

CAS 869185-85-3
Molecular Formula C21H17ClFN3OS

Specifications

Quantity 10 mg
Formula Weight 413.89
Purity >98%
Molecular Weight (g/mol) 413.90
Chemical Name or Material SB 203580 hydrochloride

Safety and Handling

Recommended Storage Desiccate at -20°C
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