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Tocris Bioscience™ SB 224289 hydrochloride
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Catalog No. 122150
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12-215-0 50 mg
12-211-0 10 mg
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Catalog No. 12-215-0 Supplier Tocris Bioscience™ Supplier No. 1221/50
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Description

Selective 5-HT1B antagonist

SB 224289 hydrochloride is a selective 5-HT1B receptor antagonist (pKi = 8.2). Displays > 60-fold selectivity over 5-HT1D, 5-HT1A, 5-HT1E, 5-HT1F, 5-HT2A and 5-HT2C receptors in radioligand binding and functional assays. Centrally active following oral administration in vivo.

Specifications

Chemical Name or Material 1'-Methyl-5-[[2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)biphenyl-4-yl]carbonyl]-2,3,6,7-tetrahydrospiro[furo[2,3-f]indole-3,4'-piperidine hydrochloride
CAS 180084-26-8
Assay Percent Range >95%
Quantity 50 mg
Solubility Soluble to 10mM with gentle warming in DMSO
Molecular Formula C32H32N4O3.HCl
Formula Weight Observed MW: 557.09

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