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SB 225002, Tocris Bioscience™ Available on GSA/VA Contract for Federal Government customers only.

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Quantity:
10mg
50mg
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182498-32-4
C13H10BrN3O4
352.144
MQBZVUNNWUIPMK-UHFFFAOYSA-N
1-2-bromophenyl-3-2-hydroxy-4-nitrophenyl urea,n-2-bromophenyl-n'-2-hydroxy-4-nitrophenyl urea,3-2-bromophenyl-1-2-hydroxy-4-nitrophenyl urea,n-2-hydroxy-4-nitrophenyl-n′-2-bromophenyl urea,d0e9bu,d0f6wv,d0t2ad,gtpl833,n-2-hydroxy-4-nitrophenyl-n'-2-bromophenyl urea,p 1-6-hydroxymethylpterin-p 2-5'-adenosyl diphosphate
3854666
1-(2-bromophenyl)-3-(2-hydroxy-4-nitrophenyl)urea
C1=CC=C(C(=C1)NC(=O)NC2=C(C=C(C=C2)[N+](=O)[O-])O)Br
This item is not returnable. View return policy
182498-32-4
C13H10BrN3O4
352.144
MQBZVUNNWUIPMK-UHFFFAOYSA-N
1-2-bromophenyl-3-2-hydroxy-4-nitrophenyl urea,n-2-bromophenyl-n'-2-hydroxy-4-nitrophenyl urea,3-2-bromophenyl-1-2-hydroxy-4-nitrophenyl urea,n-2-hydroxy-4-nitrophenyl-n′-2-bromophenyl urea,d0e9bu,d0f6wv,d0t2ad,gtpl833,n-2-hydroxy-4-nitrophenyl-n'-2-bromophenyl urea,p 1-6-hydroxymethylpterin-p 2-5'-adenosyl diphosphate
3854666
1-(2-bromophenyl)-3-(2-hydroxy-4-nitrophenyl)urea
C1=CC=C(C(=C1)NC(=O)NC2=C(C=C(C=C2)[N+](=O)[O-])O)Br

Potent and selective CXCR2 antagonist

Potent and selective CXCR2 chemokine receptor antagonist (IC 50 = 22 nM) that displays > 150-fold selectivity over CXCR1 receptors. Causes inhibition of IL-8 and GROα-mediated calcium mobilization in HL60 cells (IC 50 values are 8 and 10 nM respectively). Prevents IL-8-induced neutrophil chemotaxis in vitro and sequestration in vivo. Inhibits HIV replication in lymphocytes and macrophages.

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Quantity 10mg
Formula Weight 352.14
Percent Purity >99%
Chemical Name or Material SB 225002

Recommended Storage : Store at Room Temperature