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Tocris Bioscience™ SB 225002

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Quantity:
10 mg
50 mg
Description
Potent and selective CXCR2 chemokine receptor antagonist (IC50 = 22 nM) that displays > 150-fold selectivity over CXCR1 receptors. Causes inhibition of IL-8 and GROα-mediated calcium mobilization in HL60 cells (IC50 values are 8 and 10 nM respectively). Prevents IL-8-induced neutrophil chemotaxis in vitro and sequestration in vivo. Inhibits HIV replication in lymphocytes and macrophages.
Specifications
Specifications
Quantity | 50 mg |
Formula Weight | 352.14 |
Purity | >99% |
Molecular Weight (g/mol) | 352.14 |
Chemical Name or Material | SB 225002 |
Safety and Handling
Recommended Storage | Store at Room Temperature |
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