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  5. Tocris Bioscience™ SB 225002

Tocris Bioscience™ SB 225002
GREENER_CHOICE

Catalog No. 272550
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Potent and selective CXCR2 antagonist

Potent and selective CXCR2 chemokine receptor antagonist (IC50 = 22 nM) that displays > 150-fold selectivity over CXCR1 receptors. Causes inhibition of IL-8 and GROα-mediated calcium mobilization in HL60 cells (IC50 values are 8 and 10 nM respectively). Prevents IL-8-induced neutrophil chemotaxis in vitro and sequestration in vivo. Inhibits HIV replication in lymphocytes and macrophages.

Chemical Identifiers

CAS 182498-32-4
Molecular Formula C13H10BrN3O4

Specifications

Quantity 50 mg
Formula Weight 352.14
Purity >99%
Molecular Weight (g/mol) 352.14
Chemical Name or Material SB 225002

Safety and Handling

Recommended Storage Store at Room Temperature
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