Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Protein Analysis Reagents
  4. Bioactive Small Molecules
  5. 68605TOC

Tocris Bioscience™ SB 290157 trifluoroacetate
GREENER_CHOICE

Catalog No. 68605TOC
Click to view available options
Quantity:
5 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Potent C3a receptor antagonist

SB 290157 trifluoroacetate is a potent C3a receptor antagonist (IC50 values are 27 - 30 nM for C3a-induced Ca2+ mobilization in vitro and ex vivo). Inhibits C3a-induced chemotaxis in human mast cell line. Also inhibits tau hyperphosphorylation in vitro. Displays anti-inflammatory effects in animal models of airway inflammation and arthritis. Also inhibits glucose-induced insulin secretion and ATP production from ex vivo human and mouse pancreatic islets. Also exhibits C3a receptor agonist activity.

Specifications

Chemical Name or Material N2-[2-(2,2-Diphenylethoxy)acetyl]-L-arginine trifluoroacetate
CAS 1140525-25-2
Quantity 5 mg
Molecular Formula C22H28N4O4.CF3CO2H
Purity 97%
Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Your feedback has been submitted: Thank you for helping us improve our website.