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Tocris Bioscience™ SB 297006
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Catalog No. 421350
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Catalog No. Quantity
42-135-0 50 mg
42-131-0 10 mg
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Catalog No. 42-135-0 Supplier Tocris Bioscience™ Supplier No. 4213/50
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Description

Potent and selective CCR3 antagonist

SB 297006 is a potent and selective CCR3 antagonist (IC50 = 39 nM). Displays 250-fold selectivity for CCR3 over other chemokine receptors, including CXCR1, CXCR2, CCR1 and CCR7 (IC50 >27 μM). Inhibits calcium mobilization induced by MCP-4, eotaxin-2 and eotaxin in RBL-2H3 cells transfected with CCR3 (IC50 values are 80, 90 and 210 nM respectively).

Specifications

Quantity 50 mg
Product Type SB 297006
Purity >99%
Molecular Weight (g/mol) 342.35
Inhibitors SB 297006

For Research Use Only

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