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  5. Tocris Bioscience™ SB 332235

Tocris Bioscience™ SB 332235
GREENER_CHOICE

Catalog No. 567110
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Potent CXCR2 antagonist

SB 332235 is a potent CXCR2 antagonist (IC50 = 7.7 nM). Exhibits 285-fold selectivity for CXCR2 over CXCR1. Reduces leukocyte numbers in synovial fluid in acute and chronic rabbit arthritis models. Also reduces synovial fluid eicosanoid and cytokine levels in a rabbit chronic arthritis model. Inhibits proliferation of AML cell lines in vitro.

Specifications

Chemical Name or Material 6-Chloro-3-[[[(2,3-dichlorophenyl)amino]carbonyl]amino]-2-hydroxybenzenesulfonamide
CAS 276702-15-9
Quantity 10 mg
Target Chemokine Receptor Antagonists
Molecular Formula C13H10Cl3N3O4S
Formula Weight 410.66
Purity >98%
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