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Tocris Bioscience™ SB 525334
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Catalog No. 321150
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50 mg
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Catalog No. Quantity
32-115-0 50 mg
32-111-0 10 mg
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Catalog No. 32-115-0 Supplier Tocris Bioscience™ Supplier No. 3211/50
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Description

Selective inhibitor of TGF-βRI

SB 525334 is a selective inhibitor of transforming growth factor-β receptor I (ALK5, TGF-βRI) (IC50 = 14.3 nM). Inhibits TGF-β1-induced smad2/3 nuclear localization and TGF-βRI-induced mRNA expression in kidney cells. Attenuates bleomycin-induced pulmonary fibrosis.

Specifications

Quantity 50 mg
Product Type SB 525334
Purity >97%
Molecular Weight (g/mol) 343.42
Inhibitors SB 525334

For Research Use Only

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