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SB 590885, Tocris Bioscience™
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Quantity:
10 mg
50 mg
Description
Potent B-Raf inhibitor (Kd = 0.3 nM). Selective for B-Raf against 46 other kinases (Ki app values are 0.16 and 1.72 nM for B-Raf and c-Raf respectively). Decreases anchorage-independent growth of melanoma cell lines. Inhibits ERK phosphorylation and proliferation in tumor cells expressing B-RafV600E.
Specifications
Quantity | 10 mg |
Formula Weight | 453.54 |
Percent Purity | >98% |
Chemical Name or Material | SB 590885 |
Safety and Handling
Recommended Storage | Store at -20°C |
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