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Tocris Bioscience™ SB 612111 hydrochloride
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Catalog No. 357310R
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Catalog No. Quantity
35-731-0R 10 mg
35-735-0R 50 mg
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Catalog No. 35-731-0R Supplier Tocris Bioscience™ Supplier No. 3573/10
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Description

Selective NOP antagonist

SB 612111 hydrochloride is a selective NOP receptor antagonist (Ki values are 0.33, 57.6, 160.5 and 2109 nM for NOP, μ-, κ- and δ-receptors respectively). Antagonizes the pronociceptive action of nociceptin (Cat. No. 0910) in an acute pain model. Potentiates the action of morphine in morphine-tolerant animals and blocks hyperalgesia in an inflammatory pain model.

Specifications

Quantity 10 mg
Molecular Formula (5 S,7 S)-7-[[4-(2,6-Dichlorophenyl)-1-piperidinyl]methyl]-6,7,8,9-tetrahydro-1-methyl-5 H-benzocyclohepten-5-ol hydrochloride
Product Type SB 612111 hydrochloride
Purity 97%
Molecular Weight (g/mol) M.W. (Observed): 454.86
Inhibitors SB 612111 hydrochloride

For Research Use Only

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