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Tocris Bioscience™ SB 674042
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Catalog No. 467310
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Catalog No. Quantity
46-731-0 10 mg
46-735-0 50 mg
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Catalog No. 46-731-0 Supplier Tocris Bioscience™ Supplier No. 4673/10
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Description

Potent and selective non-peptide OX1 antagonist

Potent and selective non-peptide orexin OX1 receptor antagonist (Kd = 3.76 nM). Exhibits 100-fold selectivity for OX1 over OX2 receptors. Has no effect at serotonergic, dopaminergic, adrenergic or purinergic receptors. Inhibits orexin 1-induced Ca2+ mobilization in CHO-DG44 cells stably transfected with the OX1 receptor.

Chemical Identifiers

CAS 483313-22-0
Molecular Formula C24H21FN4O2S

Specifications

Quantity 10 mg
Formula Weight 448.51
Molecular Weight (g/mol) 448.516
Chemical Name or Material SB 674042

Safety and Handling

Recommended Storage Store at +4°C
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